%PDF-1.4
%
1 0 obj
<<
/CreationDate (D:20200508185607+05'30')
/ModDate (D:20200606145841+08'00')
/Producer (Acrobat Distiller 10.1.10 \(Windows\); modified using iText 5.5.6 2000-2015 iText Group NV \(AGPL-version\))
/Subject (IEEE Journal of Biomedical and Health Informatics;2020;24;6;10.1109/JBHI.2019.2944865)
/Title (Pathway-Based Single-Cell RNA-Seq Classification, Clustering, and Construction of Gene-Gene Interactions Networks Using Random Forests)
/IEEE#20Issue#20ID (9108313)
/IEEE#20Article#20ID (8854213)
/IEEE#20Publication#20ID (6221020)
>>
endobj
2 0 obj
<<
/Metadata 3 0 R
/Names 4 0 R
/OpenAction <<
/D [5 0 R /XYZ 0 10000 1]
/S /GoTo
>>
/PageLabels 6 0 R
/Pages 7 0 R
/Type /Catalog
>>
endobj
3 0 obj
<<
/Length 4262
/Subtype /XML
/Type /Metadata
>>
stream
application/pdf
IEEE
IEEE Journal of Biomedical and Health Informatics;2020;24;6;10.1109/JBHI.2019.2944865
cellular heterogeneity
gene-gene interactions (GGIs) networks
functional pathways
Random Forests (RF)
single-cell RNA-Sequencing
Pathway-Based Single-Cell RNA-Seq Classification, Clustering, and Construction of Gene-Gene Interactions Networks Using Random Forests
Hailun Wang
Pak Sham
Tiejun Tong
Herbert Pang
IEEE Journal of Biomedical and Health Informatics
1814
June 2020
6
24
10.1109/JBHI.2019.2944865
1822
Acrobat Distiller 10.1.10 (Windows); modified using iText® 5.5.6 ©2000-2015 iText Group NV (AGPL-version)
2020-06-06T02:55:38-04:00
2020-06-06T14:58:41+08:00
endstream
endobj
4 0 obj
<<
/Dests 8 0 R
/EmbeddedFiles 9 0 R
>>
endobj
5 0 obj
<<
/Annots [10 0 R 11 0 R 12 0 R 13 0 R 14 0 R 15 0 R]
/Contents [16 0 R 17 0 R 18 0 R]
/CropBox [0 0 594 792]
/MediaBox [0 0 594 792]
/Parent 7 0 R
/Resources <<
/ColorSpace <<
/CS1 19 0 R
/Cs6 20 0 R
>>
/ExtGState <<
/GS2 21 0 R
/GS3 22 0 R
/GS4 23 0 R
/GS5 24 0 R
/GS8 25 0 R
>>
/Font <<
/F1 26 0 R
/F2 27 0 R
/F3 28 0 R
/F4 29 0 R
/F5 30 0 R
/F6 31 0 R
/Xi0 32 0 R
>>
/ProcSet [/PDF /Text /ImageC /ImageB /ImageI]
/Properties <<
/MC1 33 0 R
/MC2 34 0 R
/MC3 35 0 R
/MC4 36 0 R
/MC5 36 0 R
>>
/XObject <<
/Im1 37 0 R
>>
>>
/Rotate 0
/Thumb 38 0 R
/Type /Page
>>
endobj
6 0 obj
<<
/Nums [0 39 0 R]
>>
endobj
7 0 obj
<<
/Count 9
/Kids [5 0 R 40 0 R 41 0 R 42 0 R 43 0 R 44 0 R 45 0 R 46 0 R 47 0 R]
/Type /Pages
/ITXT (2.1.7)
>>
endobj
8 0 obj
<<
/Kids [48 0 R]
>>
endobj
9 0 obj
<<
/Kids [49 0 R]
>>
endobj
10 0 obj
<<
/A <<
/S /URI
/URI (https://orcid.org/0000-0003-3061-9456)
>>
/Border [0 0 0]
/C [0 1 1]
/H /I
/Rect [155.775 604.011 166.767 617.425]
/Subtype /Link
/Type /Annot
>>
endobj
11 0 obj
<<
/A <<
/S /URI
/URI (https://orcid.org/0000-0002-7896-6716)
>>
/Border [0 0 0]
/C [0 1 1]
/H /I
/Rect [495.66 604.011 506.652 617.425]
/Subtype /Link
/Type /Annot
>>
endobj
12 0 obj
<<
/A <<
/S /URI
/URI (mailto:u3005316@connect.hku.hk)
>>
/Border [0 0 0]
/C [0 1 1]
/H /I
/Rect [113.754 131.573 212.847 141.986]
/Subtype /Link
/Type /Annot
>>
endobj
13 0 obj
<<
/A <<
/S /URI
/URI (mailto:herbpang@hku.hk)
>>
/Border [0 0 0]
/C [0 1 1]
/H /I
/Rect [215.337 131.577 282.543 141.986]
/Subtype /Link
/Type /Annot
>>
endobj
14 0 obj
<<
/A <<
/S /URI
/URI (mailto:pcsham@hku.hk)
>>
/Border [0 0 0]
/C [0 1 1]
/H /I
/Rect [155.523 104.676 216.978 115.085]
/Subtype /Link
/Type /Annot
>>
endobj
15 0 obj
<<
/A <<
/S /URI
/URI (mailto:tongt@hkbu.edu.hk)
>>
/Border [0 0 0]
/C [0 1 1]
/H /I
/Rect [194.736 86.748 265.767 97.157]
/Subtype /Link
/Type /Annot
>>
endobj
16 0 obj
<<
/Filter /FlateDecode
/Length 10
>>
stream
x+ |
endstream
endobj
17 0 obj
<<
/Filter /FlateDecode
/Length 36771
>>
stream
xۮ&=r%v_O/-2Rjf$ԘUAKIXk3Wح(L2_~??e}_~//W|Rۯ~?o2>l\Gۗ'uZmۜ'_ǟ? /'?ef-৵_~Ӻ{|Ӷ?O~>ǎ՟/x%1}5bۯ
F}ojv_Ge^(.˟us\oQ_/G/z?Y}?k'ٌOy5㋶;(o0uğY?_מ(lG^^t^Ǐ(x_Ae-cLցnn]]C7omk.p[l7auuz9Ć ]at5 ,Vw_.cx@kd:vzt^+>#~!p-}b.ڨu=i{1ϸ06E%j{@EOP-+FT;zoCm}O~:72pw@b(x6sl\<0<ڶ
Dύ/17]19~j:PuPPQVpݲ_α(^<:0=F Fm"ـL m IjeSSnm?.p
{k%8V61rkN7u/m![4|^}2e\^tЯm|5`ŀFfM\]p%uU#R&
}]OHxb%ps0v:& 9?bF Մw5NR`_!&h{(Pa݄c$&pDl,ۘI-Z،-r7*ؒZLjBk_3}k' ᱬ}BEs\V+r"7WLx-ۃ9`m{ȳ`x;q5aqjn[]@(byEݠ@;;y;snȵb?PNra|ӌ "
ٮq;#2썿E8~_!
l
,ف6d]mc+,4t52WF5/&a]O@.CEř.~m#]Z.7d.;Cyfs X{77!Cm6nmV[{<[9(LwƷKo|6v.4fBD`&uPEW'N#c< axuk7t=+p`
LAXaj+K[PQ}{3EEĘD"t('?Sן|zDzkn}[KcNu#[m)QCrDxK:4cqdb-P؟Km s!}wZݼ
;&wNuVhxys>'tT=P3SM}Uj(;6
HoClMSHI=>dM%p:UIQ%0tV7aLm1v^8PfG
{̉ՠ8UO.afP1HCi= hL{E͏zAҡ 46q/G4$).mbtj3Ȑa+ν
*{_z{TȈq~() `/R~][B7? jC(l y!A|S띟'Z 8Z&M$M;՞ԥ֦G._uƹ%jZHKvYn߷Fy.IM,5hC~T
jU3897/X>襋F>iوYG$4SE#d&7pCX\oo֒ǐ7UlT{mvw}4{ذ95 6 jp-6T %4OLT[~մLRh=3e>;zi&>@`,TGiy'
B2/
HHۣ}'5d*/Nԙ3h[S XT Ѱ}PUؖh<N";iaH鋻Y@4nTT/|@Y>ʥ AǽIADɶ$Ī-R<b }[SJTP[uZ+;48$~Ky^s)R